Population
17 poliovirus type 3 strains isolated between 1939 and 1958, including 9 designated Saukett
Design
Preclinical
Authors
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Strain heterogeneity may affect type 3 IPV consistency; leaves open optimal strain selection for vaccine manufacture.
Considerable genetic and antigenic heterogeneity exists among poliovirus type 3 strains, including those used in inactivated poliovirus vaccine manufacture.
Minor et al. (1982) studied this question.
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