Population
Anaesthetized dogs and cats
Comparison
Stretching the left and right atria vs Intact vs bilateral vagotomy; right vs left…
Design
Preclinical
Authors
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May link left atrial receptors to ADH suppression via vagal afferents in animals; leaves open translation to human volume regulation.
Activation of left atrial receptors inhibits neurosecretory neurones in the supraoptic and paraventricular nuclei via vagal afferents, suggesting a mechanism for ADH regulation in blood volume control.
Koizumi et al. (1978) studied this question.
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