Why the study?
Does stimulation of left atrial receptors mediate the diuretic response to left atrial distension?
Population
Preclinical model (species not specified in abstract)
Comparison
Distension of the left pulmonary vein/left… vs Distension of the whole left atrium caused by…
Design
Preclinical
Authors
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Supports vagal left atrial receptor role in animal diuresis; leaves open translation to human volume regulation.
Does stimulation of left atrial receptors mediate the diuretic response to left atrial distension?
Stimulation of left atrial receptors, mediated via the vagus nerve, is a major factor in the diuretic response to left atrial distension.
Ledsome et al. (1968) studied this question.
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