Intrathoracic Impedance vs Daily Weight Monitoring for Predicting Worsening Heart Failure Events: Results of the Fluid Accumulation Status Trial (FAST)
Why the study?
Does intrathoracic impedance monitoring improve sensitivity for predicting worsening heart failure events compared to daily weight monitoring in heart failure patients with implanted devices?
Population
156 heart failure patients with implanted cardioverter-defibrillator or cardiac resynchronization therapy…
Comparison
Intrathoracic impedance monitoring vs Standard heart failure monitoring using daily…
Design
Cohort, blinded fashion (for impedance recording)
Follow-up
537±312 days
Authors
Discussion
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Member takes
Implication
May enhance early detection of heart failure decompensation versus weight monitoring; hypothesis-generating and should not yet alter practice.
Structured PICO
Does intrathoracic impedance monitoring improve sensitivity for predicting worsening heart failure events compared to daily weight monitoring in heart failure patients with implanted devices?
P
Population
156 heart failure patients with implanted cardioverter-defibrillator or cardiac resynchronization therapy defibrillator devices
I
Intervention
Intrathoracic impedance monitoring (daily changes recorded by modified devices to calculate a fluid index)
C
Comparator
Standard heart failure monitoring using daily weight changes (acute weight increases of 3 lbs in 1 day or 5 lbs in 3 days)
O
Outcome
Sensitivity and unexplained detection rate for predicting adjudicated episodes of worsening heart failure occurring within 30 days
Intrathoracic impedance monitoring via implanted devices is significantly more sensitive and has fewer unexplained detections than daily weight monitoring for predicting worsening heart failure events.
Cite This Study
Abraham et al. (2011) studied this question.