Growth hormone but not gonadal steroids influence lipoprotein lipase and hepatic lipase activity in hypophysectomized rats

Female and male Sprague-Dawley rats from 20 to 65 days of age, hypophysectomized at 50 days of age and given replacement therapy with thyroxine and cortisone.

Oestradiol valerate (0.1 mg/kg per day), testosterone enanthate (1 mg/kg per day), or bovine GH (1 mg/kg per day) given by two daily subcutaneous injections or continuous infusion using osmotic minipumps for 1 week.

Hypophysectomized rats without the specific hormone treatment.

Lipoprotein lipase and hepatic lipase activities measured in heparinized plasma.surrogate