Mode of growth hormone administration influences triacylglycerol synthesis and assembly of apolipoprotein B-containing lipoproteins in cultured rat hepatocytes

Hypophysectomized female rats

Bovine growth hormone (1 mg/kg.day) administered as a continuous subcutaneous infusion (GHc) for 1 week, along with thyroxine (10 micrograms/kg.day) and cortisol (400 micrograms/kg.day)

Bovine growth hormone (1 mg/kg.day) administered as two daily subcutaneous injections (GH x 2) for 1 week, along with thyroxine and cortisol

Triacylglycerol synthesis and assembly/secretion of apolipoprotein B-containing lipoproteins (apoB-48 VLDL) in isolated short-term cultured hepatocytessurrogate