Why the study?
Does overexpression of Kv4.2 channels prevent phenylephrine-induced hypertrophy in cultured neonatal ventricular rat myocytes?
Does overexpression of Kv4.2 channels prevent phenylephrine-induced hypertrophy in cultured neonatal ventricular rat myocytes?
Overexpression of Kv4.2 channels prevents phenylephrine-induced hypertrophy in neonatal rat ventricular myocytes by normalizing action potential duration and calcium handling.
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Supports Kv4.2 modulation of hypertrophy in vitro; hypothesis-generating for in vivo remodeling.
Zobel et al. (2002) studied this question.
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