Why the study?
Does Preload recruitable work area (PRWA) provide a load-insensitive index of myocardial function after regional ischemic injury in dogs?
Population
8 conscious dogs instrumented to measure left ventricular pressure with micromanometers and myocardial…
Comparison
15 min of coronary occlusion followed by 24 h of… vs Control conditions (baseline before occlusion)
Design
Preclinical
Follow-up
24 hours of reperfusion
Authors
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PRWA tracks prolonged post-ischemic dysfunction load-insensitively in dogs; hypothesis-generating for clinical translation.
Does Preload recruitable work area (PRWA) provide a load-insensitive index of myocardial function after regional ischemic injury in dogs?
Preload recruitable work area (PRWA) provides a load-insensitive and precise index for quantifying myocardial dysfunction after regional ischemic injury.
Glower et al. (1988) studied this question.
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