Why the study?
Does pre- or postconditioning reduce infarct size and arrhythmogenesis in an in vivo rat model of ischemia-reperfusion?
Does pre- or postconditioning reduce infarct size and arrhythmogenesis in an in vivo rat model of ischemia-reperfusion?
In a rat model of ischemia-reperfusion, preconditioning provides stronger cytoprotection, but postconditioning is highly effective at abolishing reperfusion arrhythmias.
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May differentiate pre- versus postconditioning effects on infarct size versus arrhythmias in rats; leaves open clinical translation.
Kolettis et al. (2013) studied this question.
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