Population
Isolated murine right and left atria
Design
Preclinical
Authors
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Higenamine may promote tachyarrhythmia in humans; leaves open its cardiac safety and requires clinical translation studies.
Higenamine acts as a beta-1 adrenoceptor full agonist in murine atria and augments aconitine-induced tachyarrhythmia.
Kimura et al. (1994) studied this question.
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