Population
Dogs anaesthetized with pentobarbitone
Comparison
Injection of 20 mug of aconitine into the… vs Various surgical and pharmacological interventions
Design
Preclinical
Follow-up
90 min
Authors
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Does not support changes in human aconitine toxicity management; leaves open central catecholamine mediation of arrhythmias beyond this canine model.
Centrogenic cardiac arrhythmias induced by aconitine in dogs are mediated by the release of endogenous catecholamines from the adrenal glands.
Kp et al. (1969) studied this question.
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