Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 28, 2021Interactive Cardiovascular and Thoracic SurgeryOpen Access

Impact of dialysis in patients undergoing bioprosthetic aortic valve replacement

View Full Paper
Ask AI
Bookmark
Share

Why the study?

The incidence of bioprosthetic structural valve deterioration in dialysis patients undergoing aortic valve replacement compared to patients without dialysis remained to be determined.

Does dialysis increase the risk of structural valve deterioration and mortality in patients undergoing bioprosthetic aortic valve replacement?

Population

1159 patients undergoing bioprosthetic aortic valve replacement (258 propensity-matched)

Comparison

Patients with dialysis vs patients without dialysis

Design

Single-centre retrospective observational study with propensity score analysis

Follow-up

5 years

Authors

YKYuki KurodaInterventional / Structural CardiologyAMAkira MaruiKokura Memorial HospitalYAYoshio AraiTenri Hospital

Discussion

Loading...

Member takes

Overview

Dialysis patients warrant closer post-AVR surveillance for structural valve deterioration; leaves open optimal prosthesis selection pending randomized data.

Structured PICO

Does dialysis increase the risk of structural valve deterioration and mortality in patients undergoing bioprosthetic aortic valve replacement?

P
Population
1159 patients who underwent aortic valve replacement using bioprosthetic valves for aortic stenosis and/or regurgitation (propensity score matched sample n=258)
I
Intervention
Dialysis (n=134 initially, n=129 matched)
C
Comparator
No dialysis (n=1025 initially, n=129 matched)
O
Outcome
Incidence of moderate or severe bioprosthetic structural valve deteriorationhard clinical

Dialysis is associated with a significantly higher incidence of structural valve deterioration and mortality in patients undergoing bioprosthetic aortic valve replacement, suggesting careful valve selection is needed in this population.

Cite This Study

Kuroda et al. (2021) studied this question.

synapsesocial.com/papers/6a854cb335bc0eada8d593cfhttps://doi.org/10.1093/icvts/ivab106
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mechanical or biological heart valve for dialysis-dependent patients? A meta-analysis2020 · 30 citations
  2. 2Prosthetic Aortic Valve Stenosis in End-Stage Renal Failure2011 · 12 citations
  3. 3Accelerated Progression and Morbidity in Patients With Aortic Stenosis on Chronic Dialysis2005 · 63 citations
  4. 4Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement2017 · 693 citations
  5. 5Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)2017 · 531 citations