Why the study?
Does a high saturated fat diet impair flow-mediated dilatation compared to high PUFA, MUFA, or high-carbohydrate diets in healthy subjects?
Does a high saturated fat diet impair flow-mediated dilatation compared to high PUFA, MUFA, or high-carbohydrate diets in healthy subjects?
A high saturated fat diet impairs endothelial function (measured by flow-mediated dilatation) and increases inflammatory markers compared to high unsaturated fat or high-carbohydrate diets in healthy subjects.
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High-SFA diets impair endothelial function in healthy adults; supports replacing SFA with unsaturated fats or carbohydrates per guidelines.
Keogh et al. (2005) studied this question.
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