Why the study?
Does distension of the pulmonary vein-atrial junction reduce water intake in conscious dogs?
Population
Trained conscious dogs with a chronically implanted inflatable balloon in a left pulmonary vein at its…
Comparison
Distension of a left pulmonary vein via balloon… vs Uninflated balloon state / baseline, and…
Design
Preclinical
Follow-up
24 hours
Authors
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Pulmonary vein stretch may modulate fluid balance in dogs; leaves open translation to human volume regulation or HF therapies.
Does distension of the pulmonary vein-atrial junction reduce water intake in conscious dogs?
Distension of pulmonary vein-atrial junction stretch receptors inhibits water intake and increases urine flow in conscious dogs, suggesting a role in fluid homeostasis.
Moore‐Gillon et al. (1982) studied this question.
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