Why the study?
Does the degree of ACE inhibition correlate with plasma aldosterone concentrations in essential hypertensive patients?
Population
25 essential hypertensive patients
Comparison
Angiotensin-converting enzyme inhibitor treatment vs Hypertensive patients treated with medication…
Design
Cohort
Authors
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Aldosterone rise with ACE inhibitor duration appears independent of inhibition intensity; leaves open whether this warrants adjunctive therapy or alters long-term outcomes.
Does the degree of ACE inhibition correlate with plasma aldosterone concentrations in essential hypertensive patients?
Plasma aldosterone concentrations tend to increase with the duration of ACE inhibitor treatment in hypertensive patients, a phenomenon independent of the degree of ACE inhibition.
Sato et al. (2000) studied this question.
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