Population
poliovirus-infected cells
Design
Preclinical
Authors
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Protein 2C likely anchors poliovirus RNA to replication membranes; extends mechanistic models but leaves open antiviral translation.
The study identifies the role of poliovirus P2 proteins, specifically 2C, in attaching viral RNA to vesicular membranes for replication.
Bienz et al. (1990) studied this question.
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