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December 1, 1976The Journal of PhysiologyOpen Access

The force generated by a visceral smooth muscle.

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Population

Strips of taenia coli from the caecum of the guinea-pig (n=10)

Design

Preclinical

Authors

GGGiorgio GabellaThe London College

Discussion

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Implication

Quantifies high force output in animal visceral smooth muscle; extends basic physiology but leaves clinical relevance open.

Structured PICO

P
Population
Strips of taenia coli from the caecum of the guinea-pig (n=10)
I
Intervention
Isometric contractions elicited with 10(5)M carbachol
O
Outcome
Maximal force producedsurrogate

Visceral smooth muscle generates a large force, which may be partly explained by the lateral attachment of contractile units to the collagen network.

Cite This Study

Giorgio Gabella (1976) studied this question.

synapsesocial.com/papers/6a856ec2425e2f70a4671765https://doi.org/10.1113/jphysiol.1976.sp011628
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Force-Velocity and Series Elastic Characteristics of Smooth Muscle from the Hog Carotid Artery1974 · 72 citations
  2. 2Potassium accumulation in smooth muscle and associated ultrastructural changes1973 · 146 citations
  3. 3A filamentous cytoskeleton in vertebrate smooth muscle fibers.1976 · 258 citations
  4. 4Distribution and kinetics of CoEDTA in smooth muscle, and its use as an extracellular marker1969 · 144 citations
  5. 5Some Mechanical Aspects of an Intestinal Smooth Muscle1965 · 51 citations