Key result
A novel cardiometry methodology using a single aortic ECG lead can assess an athlete's conditioning and physiological state by evaluating parameters like lactate and creatine phosphate before and after exercise.
Why the study?
Does low-dose amiodarone cause sinoatrial node dysfunction in patients with atrial fibrillation and ventricular ectopy?
Does low-dose amiodarone cause sinoatrial node dysfunction in patients with atrial fibrillation and ventricular ectopy?
Even a low maintenance dose of amiodarone (100 mg/day) can induce symptomatic sinoatrial node dysfunction and sick sinus syndrome.
Hypothesis-generating for single-lead aortic ECG cardiometry in athletes; larger prospective studies needed before adoption.
We recently treated a case similar to that reported by Mun et al and Chinushi M. Holter ECG demonstrated paroxysmal atrial fibrillation, frequent ventricular ectopy’s, atrial tachycardia. The patient complained of palpitation. We have prescribed and amiodarone (100 mg/day) per day for 2 months. In the second visit, the palpitation attacks were relieved. It was effective in decreasing palpitation and atrial fibrillation. However, the patient was readmitted because of a new complaint of feeling weak, dizziness, confusion, and fainting. Holter monitoring revealed a long sinus pause (4–7,9 seconds). Because such a sinus pause had not been observed before the amiodarone treatment, it is likely that the development of sick sinus syndrome was related to amiodarone. Therefore, it seems inappropriate to apply this incidence of amiodarone-related sinoatrial node dysfunction to patients who are prescribed amiodarone for the treatment of ventricular tachyarrhythmia and atrial fibrillation who have prescribed a lower maintenance dose of amiodarone.
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Ayurzana et al. (2022) studied Athlete conditioning (n=2). Cardiometry assessment was evaluated on Physiological parameters (lactate, creatine phosphate, RV1) before and after physical exercise. A novel cardiometry methodology using a single aortic ECG lead can assess an athlete's conditioning and physiological state by evaluating parameters like lactate and creatine phosphate before and after exercise.
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