Why the study?
Does tyramine infusion compared to cold exposure affect blood pressure and plasma catecholamines differently in normal volunteers?
Does tyramine infusion compared to cold exposure affect blood pressure and plasma catecholamines differently in normal volunteers?
Tyramine exerts its pressor effect mainly by stimulating cardiac beta-receptors, leading to a smaller rise in plasma norepinephrine compared to the physiological sympathetic stimulus of cold exposure.
Authors
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Tyramine responses should not be equated with physiological sympathetic activation in research models; leaves open optimal stimuli for studying pressor mechanisms.
Scriven et al. (1984) studied this question.
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