Why the study?
Does angiotensin infusion alter the pressor response to tyramine in normotensive subjects and patients with essential or renovascular hypertension?
Population
32 subjects including 11 normotensive subjects, 11 patients with essential hypertension, and 10 patients…
Comparison
Intravenous infusion of angiotensin. vs Baseline pressor responses before angiotensin…
Authors
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Supports high endogenous angiotensin in renovascular hypertension; leaves open whether tyramine testing aids diagnosis or requires prospective validation.
Does angiotensin infusion alter the pressor response to tyramine in normotensive subjects and patients with essential or renovascular hypertension?
The lack of a potentiating effect of exogenous angiotensin on the tyramine pressor response in renovascular hypertension suggests high endogenous angiotensin levels due to increased renin secretion.
Kaneko et al. (1966) studied this question.
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