Why the study?
Does carvedilol reduce premature ventricular contractions in patients with hypertension, stable angina, or congestive heart failure?
Does carvedilol reduce premature ventricular contractions in patients with hypertension, stable angina, or congestive heart failure?
Carvedilol therapy significantly reduces premature ventricular contractions across a range of patients with hypertension, angina, or heart failure, without significant proarrhythmic effects.
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Carvedilol may reduce PVC burden in these patients; leaves open whether randomized trials will confirm benefit or alter practice.
Senior et al. (1992) studied this question.
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