Why the study?
Is ventilation ineffective during exercise in patients with chronic congestive heart failure compared to healthy controls?
Population
13 patients with treated chronic congestive heart failure and 8 healthy controls; all non-smokers with no…
Comparison
Maximal bicycle ergometer test with continuous… vs Healthy controls undergoing the same exercise test
Design
Case-control
Authors
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Elevated exercise dead-space ventilation may contribute to dyspnea in CHF; hypothesis-generating for targeted ventilatory interventions.
Is ventilation ineffective during exercise in patients with chronic congestive heart failure compared to healthy controls?
Patients with chronic congestive heart failure exhibit pathologically increased wasted ventilation during exercise, which correlates with disease severity and likely contributes to exertional breathlessness.
Sovijärvi et al. (1992) studied this question.
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