January 23, 2006European Heart Journal
Left ventricular dyssynchrony and dynamic functional mitral regurgitation: relationship or association?The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.
Key result
Left ventricular dyssynchrony at rest was associated with worsening functional mitral regurgitation during exercise, with roughly 20% of patients with significant dyssynchrony developing a large increase.
Population
70 heart failure patients with severe left ventricular systolic dysfunction; half of the population had…
Design
Editorial
Authors
Discussion
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Implication
Left ventricular dyssynchrony at rest is associated with the worsening of functional mitral regurgitation during exercise in patients with systolic heart failure, highlighting the clinical value of dynamic echocardiographic testing.
Structured PICO
P
Population
70 heart failure patients (half with ischaemic cardiomyopathy) evaluated for the relationship between left ventricular dyssynchrony and exercise-induced changes in functional mitral regurgitation.
O
Outcome
Exercise-induced changes in functional mitral regurgitationsurrogate
Left ventricular dyssynchrony at rest is associated with the worsening of functional mitral regurgitation during exercise in patients with systolic heart failure, highlighting the clinical value of dynamic echocardiographic testing.
Limitations
- Pulsed-wave Doppler tissue imaging does not allow assessment of regional timing differences during a single beat and is technically challenging to catch during exercise.
- Pulsed-wave Doppler tissue imaging does not allow assessment of regional timing differences during a single beat and is technically challenging to catch during exercise
Cite This Study
Piérard et al. (2006) conducted an editorial in heart failure (n=70). Left ventricular dyssynchrony at rest vs. Absence of significant left ventricular dyssynchrony was evaluated on Exercise-induced changes in functional mitral regurgitation. Left ventricular dyssynchrony at rest was associated with worsening functional mitral regurgitation during exercise, with roughly 20% of patients with significant dyssynchrony developing a large increase.