Why the study?
Does dopexamine improve creatinine clearance, systemic inflammation, and splanchnic oxygenation in patients undergoing coronary artery bypass grafting?
Population
44 patients scheduled for coronary artery bypass grafting (CABG)
Comparison
Continuous infusions of dopexamine at 0.5, 1.0… vs Placebo prior to surgery, intraoperatively, and…
Design
RCT, randomized
Follow-up
postoperatively
Authors
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Perioperative dopexamine supports renal function and attenuates inflammation in CABG; extends its perioperative evaluation in cardiac surgery.
Does dopexamine improve creatinine clearance, systemic inflammation, and splanchnic oxygenation in patients undergoing coronary artery bypass grafting?
In patients undergoing CABG, perioperative dopexamine infusion improves creatinine clearance and reduces systemic inflammation without affecting splanchnic oxygenation.
Berendes et al. (1997) studied this question.
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