Key result
Trimetazidine improves symptoms, ventricular function, and prognosis in patients with heart failure by shifting metabolism towards carbohydrate oxidation.
Why the study?
Does trimetazidine improve symptoms, ventricular function, and prognosis in patients with heart failure?
Population
Patients with heart failure
Design
Review
Authors
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Cautions against routine HF use; leaves open metabolic modulation pending large randomized trials.
Does trimetazidine improve symptoms, ventricular function, and prognosis in patients with heart failure?
Trimetazidine may be a useful adjunct to standard pharmacological treatment for heart failure by shifting myocardial metabolism to improve contractile function and prognosis.
Napoli et al. (2009) conducted a review in Heart failure. Trimetazidine was evaluated. Trimetazidine improves symptoms, ventricular function, and prognosis in patients with heart failure by shifting metabolism towards carbohydrate oxidation.
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