Key result
Among patients with type B aortic dissection, the overall prevalence of metabolic syndrome was 38.4%, with hypertension, high fasting glucose, and obesity being the most common abnormalities.
Why the study?
The study aimed to detect the prevalence of metabolic syndrome and its components and assess their association with type B aortic dissection in Chinese patients.
Cross-Sectional (n=445)
No
Metabolic syndrome is highly prevalent (38.4%) in patients with type B aortic dissection, driven primarily by hypertension, high fasting glucose, and obesity.
Supports metabolic syndrome screening consideration in type B aortic dissection; leaves open whether modification improves outcomes.
Background/Objective: The aim of this study is to detect the prevalence of metabolic syndrome (MS) and its components in type B aortic dissection patients. This study assessed the association of MS and its component with type B aortic dissection in Chinese patients.Methods: This cross-sectional prospective observation study consisted of 445 patients who were first diagnosed with type B aortic dissection. Demographic information, clinical symptoms and laboratory parameters were collected using a standard form.Results: Among the 445 TBAD patients 38.4% had MS. Hypertension was present in 78.2% of all TBAD patients. Hypertension, high fasting glucose and obesity were the most common combination of metabolic abnormalities (93%, 79.5% and 63.2%) in the TBAD patients, and a same phenomenon was seen in acute TBAD patients. But among chronic TBAD patients the most frequent individual components were hypertension, hyper- triglyceride and high fasting glucose (92.6%, 75%, and 70.6%). Presence of two or more components of the metabolic syndrome was common: 22.7% had one component, 31.9% had two components, 24.9% had three components, 10.8% had four components and 3.1% had five components. In TBAD, hypertension, obesity, triglycerides and FBG (fasting blood-glucose) were main risk factors for MS.ConclusionThis is the first study provided information on the prevalence and components of MS in the initial TBAD patients. Hypertension, high fasting glucose and obesity were the most common combination of metabolic abnormalities in TBAD patients.
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Li et al. (2020) conducted a cross-sectional in Type B aortic dissection (n=445). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Prevalence of metabolic syndrome. Among patients with type B aortic dissection, the overall prevalence of metabolic syndrome was 38.4%, with hypertension, high fasting glucose, and obesity being the most common abnormalities.
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