Why the study?
Does enalapril maleate, alone or in combination with hydrochlorothiazide, reduce blood pressure in patients with mild to moderate hypertension?
Does enalapril maleate, alone or in combination with hydrochlorothiazide, reduce blood pressure in patients with mild to moderate hypertension?
Enalapril maleate, an investigational ACE inhibitor, effectively reduces blood pressure alone and has a synergistic effect when combined with hydrochlorothiazide.
Authors
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Supports combined use in mild-moderate hypertension; leaves open outcome benefits and generalizability in larger trials.
Vlasses et al. (1983) studied this question.
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