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Does swimming training alter the hypotensive effects of the angiotensin II type 1 receptor antagonist TCV-116 in young rats?
Does swimming training alter the hypotensive effects of the angiotensin II type 1 receptor antagonist TCV-116 in young rats?
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Exercise (swimming training) may help stabilize blood pressure in young rats undergoing chronic treatment with an angiotensin II type 1 receptor antagonist.
The hypotensive effects of an angiotensin II type 1 receptor antagonist TCV-116 were accelerated by swimming training in the early period of chronic administration in young rats. In the latter period, however, a severe decrease in blood pressure that appeared during long-term administration of TCV-116 was prevented by swimming training. Therefore exercise may contribute to the stabilization of blood pressure in young rats treated with TCV-116.
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Fujii et al. (1998) studied this question.
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