January 1, 1955Annals of Internal Medicine

Oral Administration of a Potent Carbonic Anhydrase Inhibitor ("Diamox"). Iii. Its Use as a Diuretic in Patients With Severe Congestive Heart Failure Due to Cor Pulmonale

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Why the study?

Does oral acetazolamide improve diuresis in patients with severe congestive heart failure due to cor pulmonale?

Population

Patients with severe congestive heart failure due to cor pulmonale

Design

Other

Authors

ARArnold S. RelmanHarvard University ALAlexander LeafMinneapolis VA Health Care System

Discussion

Member takes

Implication

Should not change current HF practice; leaves open modern trials of acetazolamide in cor pulmonale.

Structured PICO

Does oral acetazolamide improve diuresis in patients with severe congestive heart failure due to cor pulmonale?

Population

Patients with severe congestive heart failure due to cor pulmonale

Intervention

Oral carbonic anhydrase inhibitor (acetazolamide)

This early 1955 paper discusses the rationale and initial use of oral carbonic anhydrase inhibitors (acetazolamide) as diuretics in patients with severe heart failure secondary to cor pulmonale.

Cite This Study

Relman et al. (1955) studied this question.

synapsesocial.com/papers/6a85cb6002a1bc3ea31e792a https://doi.org/10.7326/0003-4819-42-1-79

Topics

Heart failure HFrEF treatment

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Oral Administration of a Potent Carbonic Anhydrase Inhibitor ("Diamox"). Iii. Its Use as a Diuretic in Patients With Severe Congestive Heart Failure Due to Cor Pulmonale

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Oral Administration of a Potent Carbonic Anhydrase Inhibitor ("Diamox"). Iii. Its Use as a Diuretic in Patients With Severe Congestive Heart Failure Due to Cor Pulmonale

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider