Population
Rabbit polymorphonuclear leukocytes and platelets at concentrations of 5 X 10 PMN and 3.5 X 10 platelets/ml…
Design
Preclinical
Authors
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Does not support clinical use of AGEPC antagonists; leaves open its role in human thromboinflammation pending in vivo validation.
This preclinical study demonstrates that FMLP-stimulated PMNs induce platelet aggregation primarily through the generation of AGEPC.
Oda et al. (1986) studied this question.
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