July 1, 2014The International Journal of Biological MarkersOpen Access

Serum ANGPTL2 Levels Reflect Clinical Features of Breast Cancer Patients: Implications for the Pathogenesis of Breast Cancer Metastasis

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Why the study?

Do serum ANGPTL2 levels reflect clinical features of breast cancer progression and metastasis?

Population

Breast cancer patients, healthy subjects, and MDA-MB231 breast cancer cells/xenograft models

Authors

MEMotoyoshi EndoUniversity of Occupational and Environmental Health Japan YYYutaka YamamotoJikei University School of Medicine MNMasahiro NakanoGifu Prefectural General Medical Center

Discussion

Member takes

Implication

Hypothesis-generating for ANGPTL2 as metastasis biomarker; prospective validation required before any clinical role.

Structured PICO

Do serum ANGPTL2 levels reflect clinical features of breast cancer progression and metastasis?

Population

Breast cancer patients (metastatic, ductal carcinoma in situ, non-metastatic invasive ductal carcinoma), healthy subjects, and MDA-MB231 breast cancer cells/xenograft models

Comparator

Healthy subjects, patients with ductal carcinoma in situ, or non-metastatic invasive ductal carcinoma

Outcome

Serum ANGPTL2 levels and correlation with clinical features of breast cancer progression and metastasissurrogate

Serum ANGPTL2 levels may serve as a potential biomarker for breast cancer metastasis and progression.

Cite This Study

Endo et al. (2014) studied this question.

synapsesocial.com/papers/6a86556dbc4cc88ab58334c2 https://doi.org/10.5301/jbm.5000080

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Bookmark

Serum ANGPTL2 Levels Reflect Clinical Features of Breast Cancer Patients: Implications for the Pathogenesis of Breast Cancer Metastasis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Serum ANGPTL2 Levels Reflect Clinical Features of Breast Cancer Patients: Implications for the Pathogenesis of Breast Cancer Metastasis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider