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January 1, 2000Seminars in Liver Disease

Hepatitis C Virus RNA Codes for Proteins and Replicates: Does It also Trigger the Interferon Response?

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ABAndrea D. BranchIcahn School of Medicine at Mount Sinai

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Implication

Informs HCV vaccine and antiviral targets; leaves open whether dsRNA immunity can be harnessed clinically.

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Key points are not available for this paper at this time.

Cite This Study

Andrea D. Branch (2000) studied this question.

synapsesocial.com/papers/6a86640ab81bbc5ca863a00b https://doi.org/10.1055/s-2000-9502

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Hepatitis C Virus Replicons Escape RNA Interference Induced by a Short Interfering RNA Directed against the NS5b Coding Region2005 · 205 citations
2The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins2003 · 68 citations
3RNA Structural Elements of Hepatitis C Virus Controlling Viral RNA Translation and the Implications for Viral Pathogenesis2012 · 34 citations
4Hepatitis C virus internal ribosome entry site‐mediated translation is stimulated by <i>cis</i>‐acting RNA elements and <i>trans</i>‐acting viral factors2008 · 27 citations
5Interaction of Hepatitis C Virus Core Protein with Viral Sense RNA and Suppression of Its Translation1999 · 177 citations