The susceptibility of 14 human isolates of Candida albicans to commercially available vaginal douche materials and to the essential oil of Origanum syriacum was investigated in hamsters. The essential oil of O. syriacum reduced the colonization and adaptability of the C. albicans more than the commercial douche materials (p < 0.05). In addition, a dilution of the Origanum syriacum essential oil in a water solution of dimethyl sulfoxide resulted in complete elimination of C. albicans from hamster's vagina in comparison to untreated controls (p < 0.05).
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Kassaify et al. (2008) studied this question.
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