Why the study?
Does methylmethacrylate monomer produce direct relaxation of vascular smooth muscle in vitro?
Population
Segments of human saphenous vein or rabbit thoracic aorta cut into rings
Design
Preclinical
Authors
Loading...
May explain cement-related hypotension; leaves open in vivo relevance and clinical translation.
Does methylmethacrylate monomer produce direct relaxation of vascular smooth muscle in vitro?
Methylmethacrylate monomer produces direct relaxation of vascular smooth muscle, suggesting a mechanism for the severe hypotension observed during orthopedic procedures using acrylic bone cement.
Karlsson et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: