Why the study?
Does abrupt discontinuation of heparin cause early reactivation of ischaemia in patients with acute myocardial infarction treated with thrombolysis?
Population
6 patients with acute myocardial infarction treated with alteplase thrombolysis and concomitant aspirin…
Comparison
Abrupt discontinuation of intravenous heparin… vs Immediate reinfusion of heparin
Design
Case_series
Authors
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May signal rebound ischaemia after abrupt heparin cessation post-thrombolysis; hypothesis-generating and should not yet change practice.
Does abrupt discontinuation of heparin cause early reactivation of ischaemia in patients with acute myocardial infarction treated with thrombolysis?
Abrupt discontinuation of heparin after thrombolysis for acute myocardial infarction may lead to early reactivation of ischaemia, which can be reversed by immediate reinfusion.
Tano et al. (1995) studied this question.
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