Why the study?
Does restricted reflow delay or prevent reperfusion-induced arrhythmias in isolated rat hearts?
Population
Isolated rat hearts, in which left and right coronary arteries were perfused independently, subjected to…
Comparison
Restricted reflow profiles during 10 min of… vs Immediate restoration of 100% flow which was…
Design
Preclinical
Follow-up
10 minutes
Authors
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Delays VF onset without lowering incidence in isolated rat hearts; leaves open translation to in vivo or clinical reperfusion arrhythmias.
Does restricted reflow delay or prevent reperfusion-induced arrhythmias in isolated rat hearts?
In isolated rat hearts, restricted reflow delays the onset of reperfusion-induced ventricular fibrillation but does not reduce its overall incidence.
Ibuki et al. (1992) studied this question.
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