Why the study?
Does olanzapine compared to risperidone induce electrocardiographic changes in patients?
Does olanzapine compared to risperidone induce electrocardiographic changes in patients?
Both olanzapine and risperidone induce significant electrocardiographic changes, with risperidone causing QT prolongation and olanzapine causing QT shortening.
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Risperidone warrants QTc monitoring; extends RCT evidence on opposing QTc effects among atypical antipsychotics.
Shafti et al. (2014) studied this question.
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