Why the study?
Little is known regarding sex differences and temporal trends in hospitalization for catheter ablation of AF in the real-world setting.
Are there sex differences and temporal trends in the clinical profile and safety of catheter ablation for non-valvular atrial fibrillation?
Are there sex differences and temporal trends in the clinical profile and safety of catheter ablation for non-valvular atrial fibrillation?
While catheter ablation for AF is equally safe in both sexes, women undergoing the procedure have higher and more rapidly increasing CHA2DS2-VA scores compared to men, highlighting a sex disparity in clinical profiles.
Comparable safety supports AF ablation across sexes despite higher female CHA2DS2-VA scores; leaves open sex-specific risk adjustment in real-world practice.
Background: There exist sex differences in the clinical profile, management, and outcome of atrial fibrillation (AF). Catheter ablation of AF has become a first-line therapy and has markedly made headway over recent decades. Little is known about sex differences and temporal trends in hospitalization for catheter ablation of AF in the real-world setting. Conclusions: Safety of catheter ablation for AF were comparable in both sexes. In contrast, the women showed a higher CHA2DS2-VA score compared with the men. The percentage of patients with CHA2DS2-VA score ≥2 increased more quickly in women than men. Further sex-specific research is warranted to reduce this sex disparity.
No takes yet. Share an insight, caveat, or question.
Peng et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: