Why the study?
Sex differences exist in the clinical profile, management, and outcome of AF, but little is known about sex differences and temporal trends in hospitalization for AF catheter ablation in the real-world setting.
Are there sex differences in the clinical profile, efficacy, and safety of catheter ablation for non-valvular atrial fibrillation?
Are there sex differences in the clinical profile, efficacy, and safety of catheter ablation for non-valvular atrial fibrillation?
Women undergoing catheter ablation for AF have higher baseline stroke risk scores than men, despite comparable procedural efficacy and safety.
Supports sex-equitable AF ablation referral; extends real-world data but leaves open causal validation.
Background: There exist sex differences in the clinical profile, management, and outcome of atrial fibrillation (AF). Catheter ablation of AF has become a first-line therapy and has markedly made headway over recent decades. Little is known about sex differences and temporal trends in hospitalization for catheter ablation of AF in the real-world setting. Conclusions: Efficacy and safety of catheter ablation for AF were comparable in both sexes. In contrast, the women showed a higher CHA2DS2-VA score compared with the men. The percentage of patients with CHA2DS2-VA score ≥2 increased more quickly in women than men. Further sex-specific research is warranted to reduce this sex disparity.
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Peng et al. (2020) studied this question.
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