March 30, 1976Proceedings of the Royal Society B Biological Sciences
Electron microscopy of myosin molecules from muscle and non-muscle sources
Population
Myosin molecules from adult and embryonic vertebrate skeletal muscle, vertebrate cardiac muscle, vertebrate…
Design
Preclinical
Authors
Discussion
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Implication
Conserved myosin morphology may guide cardiac modeling; leaves open functional validation in human disease.
Structured PICO
P
Population
Myosin molecules from adult and embryonic vertebrate skeletal muscle, vertebrate cardiac muscle, vertebrate smooth muscle, invertebrate muscle, blood platelets and brain
I
Intervention
Electron microscopy using a modification of Hall's mica-replication technique
O
Outcome
Morphology and dimensions of myosin moleculessurrogate
Myosin molecules from diverse muscle and non-muscle sources share a highly conserved morphology consisting of two globular heads and a 150 nm tail.
Cite This Study
Elliott et al. (1976) studied this question.