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January 1, 1998International Journal of Cardiovascular Interventions

Plasma endothelin levels as a function of coronary artery manipulation during balloon angioplasty and high-speed rotational atherectomy

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Why the study?

Does coronary artery manipulation during balloon angioplasty or rotational atherectomy affect plasma endothelin levels?

Population

46 patients undergoing coronary intervention

Comparison

Balloon angioplasty or high-speed rotational… vs Between-group comparison and correlation with…

Design

Cohort

Follow-up

24 hours

Authors

OAOphir AvizoharEKEddy KarnieliZSZil A Shen-Orr

Discussion

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Overview

Endothelin levels after angioplasty associate with procedural intensity; leaves open whether this reflects endothelial injury or warrants outcome studies.

Structured PICO

Does coronary artery manipulation during balloon angioplasty or rotational atherectomy affect plasma endothelin levels?

P
Population
46 patients undergoing coronary intervention (35 underwent balloon angioplasty [BA] and 11 underwent rotational atherectomy [RA] followed by adjunctive balloon angioplasty)
I
Intervention
Balloon angioplasty or high-speed rotational atherectomy
C
Comparator
Between-group comparison (BA vs RA) and correlation with procedural parameters
O
Outcome
Arterial and venous blood endothelin levels measured before, immediately after, and 24 hours after the proceduresurrogate

Venous endothelin levels 24 hours after balloon angioplasty correlate with procedural parameters, suggesting a relationship with the extent of endothelial damage.

Cite This Study

Avizohar et al. (1998) studied this question.

synapsesocial.com/papers/6a86b036a810ea404bcf7ba2https://doi.org/10.1080/acc.1.2.93.98
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