Why the study?
Does precordial scanning with I 131-labeled Diodrast detect left-to-right cardiac shunts?
Population
75 patients evaluated for left-to-right cardiac shunts
Comparison
Precordial scanning using I 131-labeled Diodrast… vs Patients without cardiac shunts
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May aid noninvasive shunt detection via isotope kinetics; leaves open prospective validation versus modern imaging.
Structured PICO
Does precordial scanning with I 131-labeled Diodrast detect left-to-right cardiac shunts?
P
Population
75 patients evaluated for left-to-right cardiac shunts
I
Intervention
Precordial scanning using I 131-labeled Diodrast injected into an antecubital vein, metered by a scintillation detector
C
Comparator
Patients without cardiac shunts
O
Outcome
Time-concentration curve characteristics (build-up time and disappearance rate of isotope from the central circulation)surrogate
Precordial scanning with I 131-labeled Diodrast is a simple technique that can detect or exclude the presence of left-to-right cardiac shunts based on isotope disappearance rates.
Cite This Study
Cornell et al. (1961) studied this question.