Why the study?
Does quantitative radionuclide angiography using Tc-99m pertechnetate accurately quantify left-to-right cardiac shunts compared to the Fick method?
Population
43 subjects total: 21 patients with left-to-right shunts, 8 normal subjects, and 14 patients with aortic or…
Comparison
Quantitative radionuclide angiography using… vs Fick method
Design
Cross-sectional
Authors
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Supports noninvasive shunt quantification in select cases; leaves open prospective validation before practice change.
Does quantitative radionuclide angiography using Tc-99m pertechnetate accurately quantify left-to-right cardiac shunts compared to the Fick method?
Radionuclide angiography using Tc-99m pertechnetate provides an accurate method for quantifying left-to-right cardiac shunts, correlating highly with the Fick method, though it is limited in patients with severe valvular disease.
Anderson et al. (1974) studied this question.
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