Why the study?
Does an isotope circulation study using 131-labeled diatrizoate detect right to left shunts and assess circulation times in patients with suspected congenital heart disease or mitral valve disease?
Population
59 patients, including 42 suspected of having right to left shunts and 17 with disease of the mitral valve
Design
Case_series
Authors
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Hypothesis-generating for portable shunt detection; leaves open validation beyond this case report.
Does an isotope circulation study using 131-labeled diatrizoate detect right to left shunts and assess circulation times in patients with suspected congenital heart disease or mitral valve disease?
Isotope circulation studies using 131-labeled diatrizoate provide a useful, portable method for detecting right-to-left shunts and assessing circulation times without requiring femoral artery puncture.
Richard H. Greenspan (1959) studied this question.
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