Why the study?
Does moxonidine reduce blood pressure and provide protective effects in animal models of hypertension?
Population
Animal models of hypertension
Design
Review
Authors
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Should not yet change clinical practice; leaves open translation of I1-imidazoline agonism to human hypertension.
Does moxonidine reduce blood pressure and provide protective effects in animal models of hypertension?
Moxonidine is a centrally acting antihypertensive agent that lowers blood pressure via I1-imidazoline receptor activation and may offer additional protective effects on target organs and metabolism.
Ziegler et al. (1996) studied this question.
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