Why the study?
Does moxonidine improve blood pressure and reduce left ventricular mass compared to other antihypertensive drugs in patients with hypertension?
Population
Over 2,000 patients and volunteers with hypertension, including about 500 patients evaluated for long-term…
Comparison
Moxonidine 0.2-0.4 mg daily vs Other well-established antihypertensive drugs…
Design
Review
Follow-up
up to 6 months or long-term
Authors
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May support moxonidine in hypertension with LV mass reduction; leaves open confirmation in randomized trials.
Does moxonidine improve blood pressure and reduce left ventricular mass compared to other antihypertensive drugs in patients with hypertension?
Moxonidine is an effective and safe centrally acting antihypertensive that lowers blood pressure and reduces left ventricular mass with a favorable side effect profile.
Ollivier et al. (1994) studied this question.
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