Population
Purified rat angiotensinogen and partially purified rat renin
Design
Preclinical
Authors
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No product inhibition by des-AI-substrate in rats; leaves open in vivo feedback regulation and cross-species relevance.
The product of the renin-angiotensinogen reaction, des-AI-substrate, does not inhibit the reaction itself in rats.
Hackenthal et al. (1977) studied this question.
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