Population
In vitro human plasma renin assay and other aspartic proteinases
Design
Preclinical
Authors
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Does not inform clinical practice; leaves open translation of in vitro potency to in vivo efficacy or therapeutic use.
A novel series of ACHPA-lactam renin inhibitors demonstrated potent and selective inhibition of human plasma renin in vitro.
Williams et al. (1991) studied this question.
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