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March 1, 2025Romanian Journal of CardiologyOpen Access

Cardiac melanoma – a rare echocardiographic finding in emergency room settings

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Why the study?

Melanoma can metastasize to the heart, but presenting symptoms often mimic common cardiopulmonary diseases, leading to most cardiac metastases being diagnosed only on autopsy.

Population

One 67-year-old female with previously treated BRAF-mutated skin melanoma presenting with pulmonary edema

Design

Case report

Key result

Emergency echocardiography revealed a rare left ventricular metastatic mass in a 67-year-old female with a history of skin melanoma presenting with acute cardiopulmonary compromise.

Authors

ABAnna BumbuNPN.V. PichuginaАSА. S. Sukhotko

Discussion

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Overview

Symptomatic melanoma patients warrant cardiac metastasis consideration; case extends sparse antemortem reports but leaves screening and management open.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 67-year-old female with a history of BRAF-mutated skin melanoma who presented to the emergency room with acute respiratory and hemodynamic compromise and was found to have a left ventricular mass.
I
Intervention
Intensive therapy including analgesia, sedation, invasive mechanical ventilation, restrictive fluid management, diuretics, and hemofiltration, followed by a recommendation for immune therapy.

Cardiac metastasis from melanoma is a rare but important differential diagnosis in patients with a history of melanoma presenting with acute heart failure or hemodynamic instability.

Limitations

  • Single case report
  • Lack of histological confirmation of the cardiac mass due to patient refusal

Cite This Study

Bumbu et al. (2025) conducted a case report in Cardiac melanoma metastasis (n=1). Echocardiography was evaluated. Emergency echocardiography revealed a rare left ventricular metastatic mass in a 67-year-old female with a history of skin melanoma presenting with acute cardiopulmonary compromise.

synapsesocial.com/papers/6a86e231b712452940cba11ahttps://doi.org/10.2478/rjc-2025-0005
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