Why the study?
Antemortem diagnosis of cardiac metastasis from melanoma has historically been uncommon, but improved imaging now allows early and accurate detection.
Population
A 36-year-old man with metastatic melanoma and cardiac masses presenting with CVA
Design
Case report
Key result
Immunotherapy with nivolumab and ipilimumab stabilized extensive cardiac metastases from malignant melanoma in a 36-year-old man presenting with stroke-like symptoms.
Authors
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Supports potential role of immunotherapy in cardiac melanoma metastases; leaves open need for prospective validation.
Case Report (n=1)
No
This case highlights the importance of multimodality imaging for the rare antemortem diagnosis of cardiac melanoma metastases and demonstrates the efficacy of targeted immunotherapy in achieving disease stability.
Kotaru et al. (2023) conducted a case report in Melanoma with cardiac metastasis (n=1). Nivolumab and ipilimumab was evaluated. Immunotherapy with nivolumab and ipilimumab stabilized extensive cardiac metastases from malignant melanoma in a 36-year-old man presenting with stroke-like symptoms.
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